In this study, a bimetallic Co-Zn metal-organic framework (Co-Zn-MOF) was synthesized through solvothermal conditions by using Co2+ and Zn2+ salts, DABCO and H2BDC as the rigid ligands (DABCO= 1,4-diazabicyclo (2.2.2) octane, H2BDC=Benzene-1,4-dicarboxylic acid). This bimetallic MOF was used as a catalyst for the Knoevenagel condensation reaction and exhibited enhanced catalytic activity compared to its parents' single metal MOFs derived from DABCO and H2BDC precursors (Co-MOF and Zn-MOF) at mild reaction conditions, which could be attributed to the synergistic effect between the metal ions.

Copper (II) carboxylate, (Cu-BDC), metal-organic-framework (MOF) has been synthesized under solvo thermal conditions and used as a new adsorbent for the methane. The Lithium doping into Cu-BDC, (Li-Cu-BDC), is made by impregnating Cu-BDC with an ethanol solution of LiNO3, followed by heat treatment in vacuum. The adsorbent was characterized by X-ray diffraction (XRD), Fourier transform infrared (FT-IR), Thermo gravimetric analysis (TGA).Inductively coupled plasma atomic emission spectrometry (ICP-AES) and Brunauer-Emmet- Teller (BET) technique. The Sorption capacity of the methane on Cu-BDC and Li-Cu-BDC range of pressure 1-20 bar and at 298 K was investigated by volumetric measurement. This work shows that Li-Cu-BDC Compared with Cu-BDC has higher sorption capacity for CH4.

This work presents an experimental investigation of drug loading in metal-organic frameworks (MOFs). Porous metal organic framework [Zn2(bdc)2(dabco)] was synthesized under solvothermal conditions. Characterization of samples was studied by IR spectroscopy, X-ray powder diffraction, thermogravimetric analysis, ultraviolet–visible spectroscopy, N2 adsorption porosimetry and scanning electron microscopy. In vitro cytotoxicity assessment and IC50 values for the human hepatoma cell (HuH7) was determined by MTT assay. Two different sizes of Zn2(bdc)2(dabco) were prepared by solvothermal method under the presence and absence of modulator. The prepared samples were used for ibuprofen loading. Ibuprofen loadings of 22 and 30 % (w/w) were obtained for samples with average diagonal sizes of 250 and 100 nm, respectively. The release of ibuprofen from these materials was prolonged for 2 and 3 weeks for 250 and 100 nm samples, respectively. The results obtained in this study revealed that two significant factors, surface area and pore size, affect ibuprofen drug loading and release.

The current research seeks to introduce a new catalytic system called poly(N-isopropylacrylamide-co-2-acrylamido-2-methylpropane sulfonic acid sodium)- [Zn2(BDC)1.5(L)(DMF)], which refers to a thermo-responsive amphiphilic Zinc-MOF-paired ionic co-polymeric hydrogel, composed of poly(N-isopropylacrylamide-co-2-acrylamido-2-methylpropane sulfonic acid sodium) hydrogel and [Zn2(BDC)1.5(L)(DMF)] as a metal-organic framework. The catalytic system was constructed using free-radical polymerization at ambient temperature. Dynamic light scattering was then used to assess the temperature-responsiveness of the adsorbent and determine the hydrodynamic radii of the constructed compounds. LCST of the composite was around 56-58 ͌C. To determine the amounts of Zn metals in the prepared compound, atomic absorption spectroscopy (AAS) was used. The prepared composites were used to adsorb Methylene Blue from aqueous solutions. The results showed that p(NIPAM-co-NaAMPS)‐([Zn2(BDC)1.5(L)(DMF)]) composite had the potential to effectively adsorb the methylene blue in the solid-liquid biphasic reaction system. After the catalytic activity was completed, the adsorbent could be easily separated from the reaction media by manipulating temperature.  It could also be reused without any loss in activity.

Objective(s): In recent years, porous materials have shown good potential for adsorption due to their high surface area. Among them, hydroxyapatite (HA) is important as an inorganic material. While metal-organic frameworks (MOFs) have attracted much attention as hybrid materials consisting of organic and inorganic compounds with special propertiesMethods: In this study, Zn2(BDC)2(DABCO) MOF-HA nanocomposite (NC) was prepared by solvothermal method with precursors that are: Zn = zinc acetate dehydrates, BDC = 1,4-benzenedicarboxylate, and DABCO = 1,4-diazabicyclo [2.2.2] octane. This nanostructure was used to remove tetracycline drug from aqueous solution. Samples were characterized by Fourier Transform InfraRed (FTIR) spectroscopy to evaluate functional groups, X-Ray diffraction (XRD) analysis of crystal structure, field emission scanning electron microscope (FESEM) to determine morphology and size, BET analysis for measurement of surface area, and Ultraviolet–Visible (UV–Vis) spectroscopy to study drug adsorption. The effect of some important parameters on removal efficiency, such as drug concentration, nanocomposite amount, removal time and solution pH were studied. In order to reach best removal condition, the effect of the parameters and their interactions was optimized using the Box-Behnken Design (BBD) and the response surface methodology.Results: The synthesis of Zn2(BDC)2(DABCO) MOF-hydroxyapatite nanocomposite was confirmed using identification methods. The functional groups, crystal structure and surface area were evaluated by FTIR, XRD and BET respectively. The nanoscale size was approved by FESEM. In the optimum condition, the removal efficiency more than 98% was obtained. Conclusions: According to the results, MOF and its nanocomposite can be a good choice for tetracycline removal and have good potential for the development of different adsorbents.